PhD student: A systems analysis of rodent animal models of human disease

Function title PhD student Where Bioinformatics Laboratory, Academic Medical Center, Amsterdam Apply before July 15, 2009 Project Model organisms have been essential for improving our knowledge of human disease. Especially rodents, mainly mouse and rat, are often used for this purpose, as well as for pre-clinical trials of new drugs and toxicology screens. However, often animal models fail to mimic human disease adequately. As a consequence drugs successfully tested in animal models fail in costly clinical trials or are falsely discarded.
Goal of this project is to explore the suitability of rodents as a model organism for human disease, specifically metabolic syndrome. Since metabolic syndrome is a complex multifactorial group of metabolic conditions, a systems approach will be taken to uncover the molecular networks perturbed by disease.
Specifically, we aim to validate the similarity of a large number of rodent models for metabolic syndrome to their human counterparts. The project is tightly linked to ongoing projects in biological and clinical groups at the AMC. This project is part of the second round of the BioRange programme of the Netherlands Bioinformatics Centre (NBIC; ww.nbic.nl).
Tasks
The successful candidate will work towards a PhD degree in bioinformatics. We will build a compendium of rodent and human metabolic syndrome related gene expression datasets. We develop module-based joint analysis methods that search for conserved patterns consisting of sets of genes and sets of conditions in both rodent model and human under which they are co-expressed. These patterns are used to evaluate the molecular similarity of rodent models and their human counterpart. Conserved patterns will be further interpreted by constructing functional networks for metabolic syndrome in rodents and human. We expect methods developed and resulting conserved patterns and functional networks to be useful for elucidating the model mismatch and for increasing the predictive value of preclinical trials and toxicity screens.
Requirements
We are looking for an enthusiastic communicative team player with
• a MSc in one of the following areas: bioinformatics, computer science, engineering, statistics, physics, plus a proven interest in biology
• strong background in computer science (machine learning, graph algorithms, relational databases)
• good programming knowledge (R, C/Java/C++, SQL)
Additional conditions of employment: The appointment will be on temporary basis for a maximum period of four years. Based on a full-time appointment (36 hours per week), compensation will be according to standard salary levels for PhD students starting with a salary of € 2046,- with a yearly growth to € 2622,- gross a month. The collective employment agreement of the AMC is applicable. Additional information about the vacancy can be obtained
from: Dr. ir. P.D. Moerland Bioinformatics Laboratory Telephone number: +31 (0) 20 566 4660 E-mail address: p.d.moerland@amc.uva.nl
Contact: Applications should include a detailed curriculum vitae and a letter of motivation, and be sent to:
AMC Medical Research BV.
Mevrouw M.J.Scholtemeijer
Personeel & Organisatie, J1A-229
Postbus 22660
1100 DD Amsterdam
The Netherlands

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University of Kent
PhD Scholarships
Mathematics, Statistics and Actuarial Science
The Institute for Mathematics, Statistics and Actuarial Science
The Institute for Mathematics, Statistics and Actuarial Science will be offering two PhD Scholarships which will cover tuition fees at the Home/EU rate plus a maintenance grant at the same rate as the Research Councils (£12,960 per annum in 2008-09). Recipients will be expected to do some teaching as part of the terms of the Scholarship. The Scholarships will be offered for one year in the first instance, renewable for a maximum of three years subject to satisfactory academic performance. Candidates must hold a good Honours degree (First or 2i) or a Master's degree at merit or distinction in a relevant subject or equivalent.

The scholarship competition is open to all postgraduate research applicants. UK, EU and overseas fee paying students as well as full-time and part-time postgraduate research students are invited to apply.

Application Process
To be eligible for this scholarship, candidates must make a formal application for postgraduate research study at the University of Kent. This can be done online at: http://records. kent.ac.uk/ external/ admissions/ pgapplication. php
When candidates send their application paperwork to the University of Kent they should include a letter stating that they would like to be considered for this University of Kent scholarship.
Candidates who are interested in applying for one of these scholarships should contact Dr R J Shank at the institute of mathematics, Statistics and Actuarial Sciences via email at R.J.Shank@kent. ac.uk.
The deadline for receipt of applications is 17:00 on Friday 26 June 2009.

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QUT's School of Economics and Finance is seeking three PhD students to undertake study in the areas of behavioural economics and applied microeconometrics.

The scholarships are attached to a large international research group sponsored by the Australian Research Council, AusAid, the World Bank, the Ford Foundation and the German Labour Institute (IZA) as well as an international collaboration with European companies.

The successful applicants will work with researchers from the Australian National University and the QUT-based National Centre for Econometric Research.

They will be expected to follow standard economic PhD coursework in all fields of economics and to engage in a variety of analyses, such as handling large-scale data sets on migration in China, performing economic experiments in Australia with and without measuring heart rates, or developing a theoretical view of human decision making (including migration, network formation and attitudes towards risk and collaboration) .

Visit here
http://www.bus. qut.edu.au/ faculty/schools/ economics/

or here
http://rumici. anu.edu.au/ joomla/

Application criteria

* At least an Honours 2A or international equivalent thereof in economics or closely related subfield.
* Good verbal and written English language skills.
* A proven high ability in the use of analytical methods, as witnessed by courses in statistics/ economic modelling/game theory/mathematics, or else prior work of a high analytical quality.
* The ability to work with world-class researchers from many different countries (Australia, the United States, England, China, Indonesia, Germany) and the desire to become a research-oriented economist.

The scholarships

The school is offering three full-time scholarships to the value of $26,140 per annum (tax exempt and indexed annually) for three years. Top up scholarships and/or Research Assistant work may be available. The successful applicants will be based in Brisbane.

Application closing date

The closing date for applications is Thursday, 9 April 2009.

For more information about the research projects, please contact Professor Paul Frijters (phone (07) 3138 2947 or email p.frijters@qut. edu.au) or Associate Professor Uwe Dulleck (phone (07) 3138 9103 or email uwe.dulleck@ qut.edu.au).

For more information regarding the application process, please visit this website
http://www.bus. qut.edu.au/ faculty/schools/ economics/ research/ phdscholarships. jsp

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Politecnico di Milano, Italy

Notice of competitive examination and application form
http://pcsiwa12. rett.polimi. it/~phdweb/ eng/ammissione_ borse/bandostran ieri25.pdf

Notice of competitive examination XXV cycle
(Decree Rep. n° 651 Prot. n° 4659, 05th March 2009)
Notice of competitive examination published in the Official Gazzette N. 24, 27th March 2009

- Download the notice of the competitive examination (XXV cycle, Expiring April 30th 2009): ( .pdf )
http://pcsiwa12. rett.polimi. it/~phdweb/ eng/ammissione_ borse/fr_ ammissione_ borse.htm

-Application form: http://www.phd- admission. polimi.it

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M. Sc. Optics and Photonics

KSOP Masters Education. We believe that a Ph.D.graduate school is unlikely to be successful without the background / infrastructure and the “funneling / filtering” through a corresponding associated, interdisciplinary coordinated masters program, aiming at attracting excellent students from abroad.

36 students per year can be admitted to our masters program. The best students of the masters program are supported by the KSOP Scholarship Program. Access to the KSOP masters education is granted via an application procedure.

A study plan is developed for each individual masters student (corresponding to his/her educational background) when entering the KSOP.

The M.Sc. course is divided into four stages providing the students with the necessary prerequisites (Stage I: Introduction) , to give them a solid background on the most important topics within the wide and diverse field of Optics and Photonics (Stage II: Core Subjects) and let them acquire specialized knowledge (Stage III: Specialization) to be able to competently perform a six-month research project on a current topic of research (masters thesis). In addition, an 8-weeks industrial internship is scheduled between stages 2 and 3.

Scholarship

The KSOP scholarship amounts to 800 Euro/month for international students and 400 Euro/month for German students. Part of the scholarship is a research assistantship. Within the scope of this assistantship, you will have the opportunity to work on a research project in one of the KSOP institutes.

The scholarship is first admitted for 12 months. At the end you have to proof your successful participation in the KSOP M.Sc. Program through very good study results in order to extend the scholarship for another 12 months.
Guideline for Scholarship Application

Step 1 - Fill out the KSOP scholarship application form

You can apply for a scholarship at the KSOP Office after having applied for the program M.Sc. in Optics & Photonics. Please fill out the KSOP Scholarship application form. The application deadline for the upcoming winter semester is July 15 each year.

Please note that you have to send your scholarship documents seperately from your application to the student office, the KSOP Office or the international student office respectively.

You will receive feedback from the KSOP Office on your scholarship application after July 15.

Step 2 - Submit your application

You are required to include the following documents in your application:
- KSOP scholarship application form
- a certified copy of your qualification for university entrance (e.g. Abitur, High School Diploma, Bac.)
- a certified copy of your Bachelor degree (if the Bachelor degree is not yet available at the closing date for applications but will be completed before the registration, candidates can apply with a preliminary transcript of records)
- your CV
- proof of English language profiency: TOEFL (Test of English as a Foreign Language) with a minimum of 570 pb, 260 points cb and 88 points ibt or IELTS (International English Languag Testing System) band with a minium of 6.5
- proof of extra-curricular activities
- one or better two recommendations
- Statement of purpose

Please send the complete application preferrably via e-mail or alternatively via postal mail to:

Karlsruhe School of Optics & Photonics (KSOP),
Universität Karlsruhe (TH)
Schlossplatz 19
76131 Karlsruhe

http://www.ksop. de/fileadmin/ KSOP/download/ 03_programs/ Application_ Form_MSc_ Scholarship. pdf

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14 PhD Student Fellowships in Infection Biology of Human Pathogens (starting September 1, 2009) (Hannover)

Since 2006, the German Research Foundation (DFG) provides funding to Hannover Medical School (MHH) and the Helmholtz Centre for Infection Research (HZI) in Braunschweig to maintain an International Researchm Training Group (IRTG) together with the Karolinska Institutet in Stockholm (coordinators: Sebastian Suerbaum, Hannover, and Birgitta Henriques-Normark, Stockholm). The central aim of the programme is to
give young researchers the opportunity to perform their PhD work in the rapidly moving field of the infection biology of human microbial pathogens in a highly stimulating, competitive, international environment. The core element of the IRTG is a joint research programme centering on the question how human microbial pathogens achieve acute or persistent infection and how the host organism reacts to persistent infection. In addition, graduate students will participate in a highly interdisciplinary joint study programme.

Stipends will be 1365 €/month and are available for up to three years. It is an integral part of the programme that PhD students spend 6-12 months in one of the partner labs at the Karolinska Institute.

Candidates who hold the equivalent of a master’s or diploma degree in Biology, Biochemistry or Life Sciences, or who graduated in medicine are welcome to apply. Those applicants who are selected for interviews in a first round of screening will be asked to attend a selection workshop in Hannover to be held June 10 / 11, 2009.

The deadline for receipt of a complete application is April 30, 2009.
Applications are only accepted via the online application platform http://www.irtg1273 .mh-hannover. de

For detailed information on faculty and projects see
http://www.mh- hannover. de/4587.html

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PhD in cognitive neuroscience (Research Assistant)

Our profile:

HumTec is an interdisciplinary "project house" at RWTH Aachen University funded as part of the excellence initiative by the federal government and the state government of North-Rhine Westphalia. HumTec aims at fostering high level interdisciplinary research between the humanities/social sciences and the engineering/ natural sciences. Research at HumTec will focus on two research areas: "Values, Norms, Governance" and "Behaviour, Communication, Acceptance". The first area has a normative orientation comprising programs focusing on ethical, legal, and political aspects of technological innovations. The second area comprises programs with a strong empirical orientation focusing on cognitive, social, linguistic, and cultural aspects of new technologies.

The HumTec program “Brain, Concept, Writing” wants to study the genesis of complex literary concepts in an interdisciplinary team of researchers from the fields of literature, neuroscience and computer science.

Your profile:

Candidates for this position should have a degree in Neuroscience, Biophysics, Psychology, Medicine or another related degree.
Experience in cognitive neuroscience, functional imaging methods and statistics would be of advantage. The position is available immediately for initially 2 years and search will continue until a candidate has been selected.

Your duties and responsibilities:

The PhD position is dedicated to studying the neurofunctional production and comprehension processes of literary texts in the human brain in close cooperation with researchers of the Central Service Facility “Functional Imaging” (www.izkf.rwth- aachen.de) .

Our offer:

- The candidate will be employed as a regular employee.
- The position is to be filled as soon as possible and is for a fixed term of 2 years.
- This is a part-time vacancy (50 % of the standard weekly hours for full time employees).
- The option of undertaking a PhD is provided.
- The pay scale classification complies with the labor agreement TV-L.

In cases of equal qualification, aptitude and expertise of the applicants, female applicants will be given preferential treatment for those salary groups and careers in which females are underrepresented, unless there are preponderant reasons to give preference to another applicant.

Please refer to § 8 Article 6 of the North Rhine-Westphalian Equal Opportunities Act(Landesgleichstellu ngsgesetz NW).

RWTH Aachen University has been rewarded with the title “disability-friendly” (“Prädikat behindertenfreundli ch” ) for its efforts with respect to training and employment of severely disabled people. Applications from severely disabled people with appropriate suitability are explicitly welcome. This also applies to people with equal opportunities in accordance with § 2 SGB IX (Social Code).

Your contact person

For further information, please contact
Dr. Ralph Schnitker
Tel.: +49 (0) 241 80 88890
Fax: +49 (0) 0241 80 82605
Email: rschnitker@izkf. rwth-aachen. de

You can also obtain further information from our websites: http://humtec@ rwth-aachen. de

Please send your application via mail to

Dr. Ralph Schnitker
mail: rschnitker@izkf. rwth-aachen. de

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Our newly established multidisciplinary “aivoAALTO” research project opens positions in the field of systems-level human brain imaging and related research, with a strong focus on social interaction in natural settings, including economic decision making, cinema viewing, and methodological development.
http://www.aaltoyli opisto.info/ en/news/funding- to-aalto- university- s-aivoaalto- research- project

The project involves Helsinki University of Technology(TKK, www.tkk.fi ), Helsinki School of Economics (HSE, www.hse.fi> ) and Helsinki University of Art and Design (TAIK, www.taik.fi ).
These three schools are just merging to form a new Aalto University (“Aalto”, meaning wave, honors the famous Finnish architect Alvar Aalto).

The positions, available immediately for up to 3 years, are the following:
• 1 PhD student in neuroeconomics and decision making
• 1 PhD student in neurocinematics
• 1 PhD student in brain-imaging- related signal analysis
• 3 postdoctoral positions in human brain imaging and related research
• 2 senior scientist positions in human brain imaging and related research

For further information, see
http://neuro. ltl.hut.fi/ ~hari/aivoAALTO_ positions_ March2009. pdf

--
Riitta Hari, prof.
Brain Research Unit
Low Temperature Laboratory
Helsinki University of Technology
Puumiehenkuja 2, room #250
02015 TKK, Espoo, Finland
tel +358 9 451 2959, fax +358 9 451 3508
hari@neuro.hut. fi
http://neuro. hut.fi (Brain Research Unit)
http://ltl.tkk. fi/wiki/LTL/ Contact_informat ion (How to find us)

Advanced Magnetic Imaging Centre (AMI)
Helsinki University of Technology
http://www.ami. hut.fi

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